How Food Allergies Work and Affect the Body: Understanding the Immune Response

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An estimated 32 million Americans are affected by food allergies. These occur when the immune system misidentifies harmless food proteins as threats, triggering a complex chain of defensive responses.

The Immune Response Process

Step 1

First Exposure

Body encounters allergen and produces IgE antibodies

Step 2

Antibody Binding

IgE attaches to mast cells and basophils

Step 3

Re-exposure

Allergen recognized by IgE antibodies

Step 4

Chemical Release

Release of histamine and other chemicals

Mild Symptoms

  • • Hives and itching
  • • Swelling
  • • Stomach upset
  • • Vomiting
  • • Diarrhea

Severe Symptoms (Anaphylaxis)

  • • Difficulty breathing
  • • Drop in blood pressure
  • • Rapid heartbeat
  • • Throat swelling
  • • Loss of consciousness

Major Food Allergens

Milk
Eggs
Peanuts
Tree Nuts
Soy
Wheat
Fish
Shellfish

Diagnosis Methods

  • Medical history review
  • Physical examination
  • Skin prick tests
  • Blood tests for IgE
  • Oral food challenges

Treatment Options

  • Strict allergen avoidance
  • Emergency medication
  • Oral immunotherapy (OIT)
  • Label reading education
  • Emergency action plan

Prevention Strategies

Early Introduction

Introduce allergenic foods at 4-6 months

Breastfeeding

Recommended for first 6 months

Environment

Avoid smoke exposure and pollutants

Emergency Action

Always carry prescribed emergency medication (like epinephrine auto-injectors). Seek immediate medical attention for severe reactions or anaphylaxis.

Disclaimer: This information is for educational purposes only. Always consult with a healthcare provider for proper diagnosis and treatment of food allergies.