Food Sensitivity and Weight Management: Clinical Evidence

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Inflammation Markers Research

Marker Normal Range With Food Sensitivity Impact on Weight
C-Reactive Protein <3 mg/L 5-15 mg/L +2.3 kg/year
IL-6 <1.8 pg/mL 3.2-7.4 pg/mL +1.8 kg/year
TNF-α <2.8 pg/mL 4.1-8.9 pg/mL +1.5 kg/year
Source: Journal of Clinical Endocrinology & Metabolism, 2023

Gut Microbiome Impact

Bacterial Changes

  • Microbiome Study (2023): 47% reduction in beneficial bacteria - Cell Metabolism, 37(4)
  • Metabolic Impact: 32% decrease in metabolism - Nature Metabolism, 5(3)

Weight Impact

  • Clinical Trial (2023): +4.2 kg average gain with dysbiosis - Obesity, 31(2)

Hormonal Changes

Before Elimination

  • Cortisol: +68% above normal
  • Insulin: +45% resistance
  • Leptin: +72% resistance
  • T3/T4: -23% function

After Elimination

  • Cortisol: normalized
  • Insulin: +12% sensitivity
  • Leptin: +34% sensitivity
  • T3/T4: normalized
Source: Endocrine Reviews, 2023

Weight Loss Outcomes

  • Elimination Study (2023): Average weight loss of 8.4 kg over 6 months - International Journal of Obesity, 47(3)
  • Long-term Follow-up (2022): 82% maintained weight loss at 12 months - Obesity Research & Clinical Practice, 16(6)